FOOD SCIENCE AND TECHNOLOGY 762

Spring Quarter 1996

8:30- 9:48 AM Monday, Wednesday and Friday
Kottman Hall 102
Sylvia A. McCune, Ph.D.
256B Howlett Hall
292-6796 (Office) and 292-1090 (Lab); 761-1697 (Home)

Objectives:

  1. Know the pathways of amino acid metabolism in higher animals.
  2. Know the pathways involved in nucleic acid metabolism.
  3. Evaluate some of the ethical issues created by the introduction of some of the new molecular biology techniques.
  4. Know the processes involved in protein synthesis and degradation and the regulation of these processes.
  5. Evaluate current nutrition controversies relative to protein, nucleic acid and amino acid metabolism by examining the ethical uses of data.
  6. Understand how the interrelationships of protein, carbohydrate and fat are altered by hormones and diet.
  7. Integrate information about protein, carbohydrate and fat metabolism under various physiologic conditions.

Evaluation:

Three one-hour exams ...................... 300 points

Textbooks: None required.
Any basic biochemistry book should give enough background.
Class notes can be purchased at OSU bookstore

Office hours: Wednesday 10:00 to 11:30 am
Other times by appointment

 

General Topical Outline:

I. Protein and Amino Acid Metabolism

  1. Basic structure of proteins
  2. Protein digestion and degradation
  3. Classification of amino acids
  4. Pathways of degradation of amino acids
  5. Pathways of synthesis of non-essential amino acids
  6. Urea cycle
  7. Tissue utilization of amino groups
  8. Regulation of amino acid metabolism
  9. Specialized products synthesized from amino acids
  10. One carbon metabolism

II. Nucleic Acid Metabolism

  1. Pentose phosphate pathway
  2. Purine synthesis and degradation
  3. Pyrimidine synthesis and degradation
  4. Cross regulation of purine and pyrimidine pathways
  5. Nucleic acid components needed for protein synthesis

III. Genotype (DNA) to Phenotype (Protein)

  1. Protein synthesis
  2. Regulation of protein synthesis and degradation
  3. Molecular biology techniques and uses

IV. Integration and regulation of metabolism of protein, carbohydrate and fat

  1. Interrelationships of pathways
  2. General mechanisms of regulation
  3. Specific hormone actions
  4. Drugs and nutrient interaction