SUB-CHRONIC (90-360 DAYS)
ORAL TOXICITY
PURPOSE:
Characterize the toxicity of a substance and to define a level that produces "no observed adverse effects." NOEL
ANIMALS:
Similar to short-term tests except that twice the number of animals are used.
DOSAGE:
Continuous exposure for at least 90 days.
OBSERVATIONS:
Daily observations.
Tests similar to short-term tests with the addition of some additional organs.